The U.S. Food and Drug Administration (FDA) announced the nationwide recall of four lots of pet medication due to a contamination hazard.
Concerns about the presence of glass fibers led American Regent of Shirley, New York, to withdraw Adequan® Canine Injection for dogs and Adequan® i.m. Injection for horses, according to an FDA public health alert.
“The products are being recalled due to the presence of glass fibers found during testing of internally retained samples,” federal officials said. “The administration of an intramuscular injectable product containing particulate matter, such as glass fibers, may result in local irritation, swelling, inflammation, injection site pain, infection, or abscesses.”
Adequan Canine is a prescription medication used in the treatment of non-infectious degenerative or traumatic joint dysfunction in dogs, while Adequan i.m. is used to treat noninfectious degenerative or traumatic joint dysfunction and associated lameness in horses.
The recall is applicable to both 100 mg/mL 5mL multi-dose vials and 500mg/5 mL single-dose vials.
Both Adequan Canine and Adequan i.m. are clear and colorless to slightly yellow solutions.
The two lots of dog medication were distributed nationwide to online pharmacies, distributors, wholesalers, and veterinarians in the United States from May 22, 2024 through April 14, 2025, while the two lots of horse medication were distributed nationwide to online pharmacies, distributors, wholesalers, and veterinarians in the United States from May 8, 2025 through Jan. 22.
In a similar April recall, Revival Animal Health, based in Orange City, Iowa, announced the withdrawal of select lots of its Breeder's Edge Foster Care Canine and Shelter's Choice Canine milk replacers.
The recalled batches potentially contained dangerously inconsistent levels of Vitamin D and the error could cause serious illness or even death in young dogs, according to federal officials.
The products were sold nationwide through online retailers and brick-and-mortar pet stores in resealable bags and 12-ounce jars.
The recall is applicable to seven products across both brands, ranging from 1-pound bags of Shelter's Choice Canine Milk Replacer to 20-pound bags of Breeder's Edge Foster Care.
The issue stems from variable levels of Vitamin D during production—meaning some containers had too little while others had too much. Two complaints of rickets, a bone disease associated with Vitamin D deficiency, were reported.
While low levels are a concern, elevated Vitamin D poses a more immediate danger. According to the FDA, Vitamin D is a fat-soluble vitamin, meaning the body cannot quickly flush out excess amounts the way it does with water-soluble vitamins. Instead, it accumulates in fat tissue and the liver—and at high enough concentrations, it can trigger kidney failure and death.