Brendon Fallon is the host and executive producer of NTD's "Vital Signs," a health show that zooms in on the important matters of health that come up in everyday life—connecting the dots across the broad canvas of our holistic wellbeing.


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Discover trending health videos for body, mind, and soul on Vital Signs. Explore important matters of everyday health, from better sleep to virus immunity

Vital Signs

Nitrogen Plasma: Skin Treatment Hope for Acne Scars, Wrinkles, Sagging?

Diet Switch: Hormone, Weight Loss, Brain Health Benefits | Bella Ma

Why Women Must Build Muscle — Best Protein, Exercises | JJ Virgin

Vinegar, Rye, Steel-Cut Oats, and other Fat Busters | Jason Fung MD

Curb Hunger Hormones to Lose Weight Drug Free | Jason Fung MD

Ease Arthritis: Supplements to Surgery | Orthopedic Surgeon

Cut Kidney Inflammation Risk via the Fasting Mimicking Diet | Dr. Jason Fung

Why the ‘Biggest Losers’ Regained Weight | Dr. Jason Fung

Why Are We Fatter Now Than in the 70s? | Dr. Jason Fung

Which Foods Most Harm the Liver, Cause Diabetes? Feat. Dr. Jason Fung

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Amid America’s <a href="https://www.cdc.gov/media/releases/2024/p0912-adult-obesity.html" target="_blank" rel="nofollow noopener">obesity epidemic</a>, a drug that can commonly lower body weight by <a href="https://pubmed.ncbi.nlm.nih.gov/33567185/" target="_blank" rel="nofollow noopener">15 percent</a> is sure to be welcomed with open arms.

Accordingly, the weight-loss drug Ozempic hit <a href="https://www.biospace.com/business/10-best-selling-drugs-of-2024-rake-in-billions-amid-exclusivity-threats" target="_blank" rel="nofollow noopener">$16.9 billion</a> in sales in 2024, making it the world’s second-best-selling drug.

However, the best-selling author of “The Diabetes Code,” Dr. Jason Fung M.D., is concerned by how readily Ozempic is being dispensed to people it may be unsuitable for.

Fung joins “Vital Signs with Brendon Fallon” to explain why and when he prescribes Ozempic as a nephrologist (i.e., a kidney health specialist), and how Ozempic compares to low-carb dieting and fasting in terms of its risks and benefits.

“You can look online and there's a lot of pictures … of celebrities, and they all have this sort of gaunt ‘Ozempic face,’ which is the loss of subcutaneous fat,” he says.

“Subcutaneous fat … is the fat underneath the skin, and that’s not that dangerous … [it’s] contained within the fat cell where it’s supposed to be,” he adds.

Is Ozempic more likely to cause sagging skin than low-carb dieting or fasting would? Is it more likely to cause muscle loss?

Ozempic largely affects the GLP-1 satiety hormone, says Fung, suppressing appetite.

“But remember that Ozempic doesn't raise your GLP-1 levels to a normal physiologic level.”

“It's a super-physiological stimulus,” he says, suggesting the drug suppresses appetite to a level well beyond what nature intended.

On “Vital Signs,” Fung reveals how well weight loss is sustained after stopping Ozempic, and also which accompanying diet and lifestyle changes optimize its results.

Watch “Kidney Detox” on how the Fasting-Mimicking Diet can reduce kidney damage and restore health | Jason Fung M.D.

Watch “Probiotic Hormone Balance” on the good bacteria that can counter UTIs, STDs, and depression | William Davis M.D.

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Watch “Silent Sugar” on foods that carry a hidden diabetes risk.

Watch “Reverse Type 2 Diabetes” on the silent dietary factor driving the diabetes rise.

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<a href="https://www.primetherapeutics.com/documents/d/primetherapeutics/prime-therapeutics_glp-1-therapy-to-treat-obesity-among-members-without-diabetes_three-year-persistence?utm_source=chatgpt.com">GLP-1 Therapy to Treat Obesity Among Members Without Diabetes: Three-Year Persistence and Year-Over-Year Persistence Rate Change</a>

<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/">Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension</a>

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<em>Vital Signs’ host, guests, and contributors offer general information on improving health and wellness. This is not intended as diagnosis or medical advice. You should consult your medical doctor or holistic doctor before enacting any suggested strategies for health and wellness improvement, including those in relation to preventing or treating specific diseases featured on this program.</em>

<em>Views expressed in this video are opinions of the host and guests, and do not necessarily reflect the views of NTD.</em>

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Best Weight Loss Plan to Cut Flabby Skin, Keep Muscle, Stay Thin?