Moderna, the Cambridge, Massachusetts-based biotechnology company behind one of the first COVID‑19 vaccines, announced that it will reduce its global workforce by 10 percent by the end of 2025, according to a public memo sent to employees by CEO Stéphane Bancel.
According to Bancel, Moderna is targeting $1.5 billion in annual operating expense reductions by 2027. He said the company first attempted to cut costs by scaling down research and development programs, renegotiating supplier agreements, and lowering manufacturing expenses before deciding to implement job layoffs.
Moderna’s shares had declined more than 20 percent so far in 2025, and 90 percent lower than their pandemic-era peak. The company’s stock trading was about 4 percent lower Thursday following the layoff announcement.
Despite the cuts, Bancel emphasized that “Moderna’s mission remains unchanged.” The company currently has three approved products and plans to seek up to eight additional approvals in the next three years, with development focused on oncology, rare diseases, and latent virus vaccines, according to Bancel’s memo.
The company is also confronting changes in vaccine policy and funding. In May 2025, the Department of Health and Human Services (HHS) terminated a $766 million contract supporting Moderna’s mRNA‑1018 H5N1 bird flu vaccine program.
“The reality is that mRNA technology remains under‑tested, and we are not going to spend taxpayer dollars repeating the mistakes of the last administration, which concealed legitimate safety concerns from the public,” Nixon said.
