Fat Cells Under the Skin Can Trigger Hair Growth, Study Discovers

Researchers discovered a fatty acid hair regrowth serum that can work in three weeks.
Published: 11/11/2025, 9:44:19 AM EST
Fat Cells Under the Skin Can Trigger Hair Growth, Study Discovers
Operation theatre (OT) technicians insert follicles to a patient during a hair transplant surger at Crown clinic in New Delhi, India, on Nov. 5, 2022. (Sajjad Hussain/AFP via Getty Images)

A new study found evidence that fat cells under the skin can trigger hair growth.

The Lipolysis Activates Epithelial Stem Cells for Hair Regeneration Through Fatty Acid Metabolic Signaling study was published in Cell Metabolism magazine and documents the discovery of a fatty acid hair regrowth serum that can work in three weeks.

National Taiwan University professor Sung-Jan Lin and his team did not respond to requests for comment; however, licensed cosmetologist Hausofpretty.com founder Kelsey Morey is surprised by the fatty acid component of the discovery.

“This sets a precedent that hair growth can be regenerative just as we are discovering in the skincare industry,” Morey told NTD.

Common fatty acids can be saturated, monounsaturated, and polyunsaturated.

MedlinePlus categorizes polyunsaturated fats as a healthy dietary fat along with monounsaturated fats and recommends eating salmon, albacore tuna, herring, vegetable oils, walnuts, flax seeds, and sunflower seeds for the highest doses, while palm oil and cocoa butter, for example, contain saturated fatty acids.

The study further found that in shaved mice, induced eczema led to new hair sprouting in 10-11 days, with full coverage developing after some 20 days. The fatty acid serum achieved similar results on non-irritated skin, and hair density and thickness improved significantly with no reported side effects from the natural ingredients.

“The team has patented the formula and plans scalp dosage studies soon,” Dr. Alan Bauman of Bauman Medical in Boca Raton told NTD. “This research could revolutionize over-the-counter options for alopecia areata, pattern hair loss, or post-injury regrowth. Unlike chemical irritants, the serum’s natural profile suggests low irritation risk, making it appealing for sensitive scalps.”

Because mouse model results differ from humans in factors such as genetics and hormones, Bauman integrates treatments with adipose-derived stem cell (ADSC) therapies and growth factor applications.

The National Institutes of Health (NIH) describes ADSC therapy as a regenerative medicine method that employs stem cells from a patient's own fat tissue to promote healing and tissue repair, while growth factor applications can be administered through injections or topical applications to stimulate cell growth and repair.

"If you’re experiencing hair loss, don’t wait for experimental serums," Bauman added. "Early intervention is key. Schedule a comprehensive hair check-up to measure follicle health and density. Explore proven options like our Formula 82M compounded minoxidil or TED ultrasound delivery for growth factors and stay informed on breakthroughs, but rely on expert evaluation."