More Than 20 Aboard Oceania Insignia Sickened in GI Outbreak, CDC Says

The CDC said the cause of the outbreak has not yet been identified, and stool samples from sick passengers are undergoing testing to determine the pathogen.
Published: 4/15/2026, 11:09:38 PM EDT
More Than 20 Aboard Oceania Insignia Sickened in GI Outbreak, CDC Says
The cruise ship 'The Harmony of the Seas,' part of the Royal Caribbean International fleet, is moored at a quay in the port of Miami on Dec. 23, 2020. (Daniel Slim/AFP via Getty Images)

More than 20 people on an Oceania Cruises voyage reported being sick from an outbreak of gastrointestinal illness, according to the Centers for Disease Control and Prevention.

According to an April 15 notice from the CDC’s Vessel Sanitation Program, 19 of 633 passengers—exactly 3 percent—and 3 of 394 crew members, or less than 1 percent, reported being sick during an April 7-14 sailing of the luxury line’s Oceania Insignia. The outbreak was reported to the CDC on April 13 and involved passengers and crew whose predominant symptom was diarrhea.

The CDC said the cause of the outbreak has not yet been identified, and stool samples from sick passengers are undergoing testing to determine the pathogen. Norovirus is a frequent culprit in cruise ship outbreaks, but the CDC noted that “we don't always know the cause of the outbreak when we begin an investigation” and that confirming an agent can take time.

In response, Oceania Cruises and the ship’s crew increased cleaning and disinfection in line with their outbreak prevention and response plan, isolated sick guests and crew, and collected stool specimens for laboratory analysis. The company also consulted with Vessel Sanitation Program officials on sanitation procedures and reporting of cases while federal staff “remotely monitored the situation, including review of the ship's outbreak response and sanitation procedures,” the agency said.

A spokesperson for the cruise line did not respond to a request for comment from NTD News prior to publication.

Cruise lines must report cases of acute gastroenteritis when passengers or crew meet the CDC’s case definition and see a shipboard doctor. The CDC defines a reportable case as three or more loose stools within 24 hours, or more than is normal for that person, or vomiting accompanied by another symptom such as diarrhea, muscle aches, headache, abdominal cramps, or fever.

The Insignia outbreak is the third gastrointestinal incident on a cruise ship tracked by the Vessel Sanitation Program so far this year. Earlier in 2026, the CDC posted outbreaks aboard Regent Seven Seas’ Seven Seas Mariner, tied to E. coli on a Jan. 11 to Feb. 1 voyage, and Princess Cruises’ Star Princess, where a March 7 to 14 sailing saw 141 of 4,307 passengers and 52 of 1,561 crew became sick with norovirus.
The new cluster comes on the heels of a busy 2025 for shipboard stomach bugs. According to the CDC, the Vessel Sanitation Program logged 23 gastrointestinal outbreaks last year on cruise voyages that included U.S. ports, mostly blamed on norovirus but with some linked to other agents such as E. coli and presumed ciguatera.

Passengers can take steps to reduce their risk by following CDC “tips for healthy cruising,” which emphasize handwashing, fast reporting of symptoms to the ship’s medical center, and following isolation instructions if they become sick.