Full Episodes

For decades, nutrition advice has emphasized fruits, vegetables, and fiber. But what if some of those long-held beliefs are wrong? On Vital Signs, physician Dr. Anthony Chaffee responds to common criticisms of the carnivore diet – from kidney stones to gout – and explains why he believes meat-based diets may reduce inflammation and improve health. The conversation raises a bigger question: are modern health problems caused by what we eat, or by what we’ve added to our food?

Depression has long been framed as a chemical imbalance – a simple matter of serotonin too low, mood too low. But the rabbit hole goes much deeper. It goes without saying that mental health, like other dimensions of the body – the gut, metabolism, and immunity, can suffer illness, said internal medicine physician Dr. Austin Perlmutter.

What if weight loss isn’t about calories? Dr. Jason Fung explains how insulin and ultra-processed foods may drive hunger.

Weight loss isn’t about calories, says Dr. Jason Fung—it’s about mastering hunger and the hormones behind it.

Protecting the brain may start with protecting its energy supply. While the use of hunger-cutting drugs, like Ozempic, for weight loss soars, scientists are probing their potential to stave off brain diseases, like Parkinson’s and Alzheimer’s.

What if there’s more to cancer treatment than ‘attacking the tumor?’ On “Vital Signs,” herbalist and certified nutritionist Donny Yance lays out a very different way of thinking about cancer — one that steps away from ‘war against tumors’ language to look at the whole person instead.

After surviving a severe autoimmune illness, Dr. Douglas Spiel focused not on performance, but on restoring his body’s ability to recover.

After a personal collapse that ended his surgical career, neurosurgeon Dr. Joseph Maroon rebuilt his life through endurance sports—and now, at 84, is pursuing a potential breakthrough in Parkinson’s disease by restoring the brain’s master antioxidant.

Pain is the leading reason Americans seek medical care, and as arthritis-driven joint damage continues to rise with age, orthopedic surgeon Dr. Nicholas DiNubile shares how prevention, supplements, and regenerative surgery can help preserve joint health and mobility.

With dementia rates set to double by 2060, neurologist Dr. David Perlmutter says the lifestyle and metabolic choices people make in midlife can shape their brain health for decades to come.

In part, depression is an energy-flow problem, says Dr. Jingduan Yang, drawing from a broad integrative-medicine playbook on how to relieve it.

The rate of autism has skyrocketed beyond what it was just a few decades ago. Are doctors better at diagnosing it, or are environmental factors at play?

From lifelong learning to living with purpose, discover nine time-honored habits that protect the brain against Alzheimer’s.

“I wound up volunteering to go up to Khe Sanh. I didn’t have any idea what I was going to encounter,” says retired Lt. Col. Allen Davies MD, recalling how he ended up in one of the most intense battle zones of the Vietnam War.

Anxiety, depression, and other mental distress can be caused by pyrrole disorder (aka pyroluria). How can this loss of zinc, Vitamin B6, and other nutrients be identified and treated?

Is Alzheimer’s disease a result of toxins that trigger brain inflammation? Can nurturing brain lymphatic flow boost toxic clearance?

Burnout may look like exhaustion, but as James Gordon suggests, it often signals a deeper rupture—where purpose, pressure, and unresolved trauma quietly collide.

What if the rise in ADHD isn’t just about diagnosis – but about what kids are eating every day? In this Vital Signs interview, Harvard-trained psychiatrist Dr. Uma Naidoo points to a growing concern: ultra-processed foods, added sugars, and nutrient-poor diets may be quietly affecting how children think and behave.

Everyday symptoms like skin rashes, joint pain, and fatigue may seem unrelated—but according to Dr. Jeffrey Bland, they could all trace back to one powerful root: the gut.

The cardio-training push for women goes back to the 60s—has the focus been off all along?

For decades, nutrition advice has emphasized fruits, vegetables, and fiber. But what if some of those long-held beliefs are wrong? On Vital Signs, physician Dr. Anthony Chaffee responds to common criticisms of the carnivore diet – from kidney stones to gout – and explains why he believes meat-based diets may reduce inflammation and improve health. The conversation raises a bigger question: are modern health problems caused by what we eat, or by what we’ve added to our food?

Depression has long been framed as a chemical imbalance – a simple matter of serotonin too low, mood too low. But the rabbit hole goes much deeper. It goes without saying that mental health, like other dimensions of the body – the gut, metabolism, and immunity, can suffer illness, said internal medicine physician Dr. Austin Perlmutter.

What if weight loss isn’t about calories? Dr. Jason Fung explains how insulin and ultra-processed foods may drive hunger.

Weight loss isn’t about calories, says Dr. Jason Fung—it’s about mastering hunger and the hormones behind it.

Protecting the brain may start with protecting its energy supply. While the use of hunger-cutting drugs, like Ozempic, for weight loss soars, scientists are probing their potential to stave off brain diseases, like Parkinson’s and Alzheimer’s.

What if there’s more to cancer treatment than ‘attacking the tumor?’ On “Vital Signs,” herbalist and certified nutritionist Donny Yance lays out a very different way of thinking about cancer — one that steps away from ‘war against tumors’ language to look at the whole person instead.

After surviving a severe autoimmune illness, Dr. Douglas Spiel focused not on performance, but on restoring his body’s ability to recover.

After a personal collapse that ended his surgical career, neurosurgeon Dr. Joseph Maroon rebuilt his life through endurance sports—and now, at 84, is pursuing a potential breakthrough in Parkinson’s disease by restoring the brain’s master antioxidant.

Pain is the leading reason Americans seek medical care, and as arthritis-driven joint damage continues to rise with age, orthopedic surgeon Dr. Nicholas DiNubile shares how prevention, supplements, and regenerative surgery can help preserve joint health and mobility.

With dementia rates set to double by 2060, neurologist Dr. David Perlmutter says the lifestyle and metabolic choices people make in midlife can shape their brain health for decades to come.

In part, depression is an energy-flow problem, says Dr. Jingduan Yang, drawing from a broad integrative-medicine playbook on how to relieve it.

The rate of autism has skyrocketed beyond what it was just a few decades ago. Are doctors better at diagnosing it, or are environmental factors at play?

From lifelong learning to living with purpose, discover nine time-honored habits that protect the brain against Alzheimer’s.

“I wound up volunteering to go up to Khe Sanh. I didn’t have any idea what I was going to encounter,” says retired Lt. Col. Allen Davies MD, recalling how he ended up in one of the most intense battle zones of the Vietnam War.

Anxiety, depression, and other mental distress can be caused by pyrrole disorder (aka pyroluria). How can this loss of zinc, Vitamin B6, and other nutrients be identified and treated?

Is Alzheimer’s disease a result of toxins that trigger brain inflammation? Can nurturing brain lymphatic flow boost toxic clearance?